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1

Population Pharmacokinetic Modelling of FE 999049, a Recombinant Human Follicle-Stimulating Hormone, in Healthy Women After Single Ascending Doses

Rose, Trine Høyer, Röshammar, Daniel, Erichsen, Lars, Grundemar, Lars, Ottesen, Johnny T.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

2

The cloned guinea pig neuropeptide Y receptor Y1 conforms to other mammalian Y1 receptors

Magnus M. Berglund, Sara K.S. Holmberg, Henrik Eriksson, Karin Gedda, Jean-Pierre Maffrand, Claudine Serradeil–Le Gal, Vijay Chhajlani, Lars Grundemar, Dan Larhammar

Journal:

Year:

1999

Language:

english

File:

PDF, 409 KB

english, 1999

3

Electroconvulsive treatment evokes release of preprotachykinin-a mRNA into the cerebrospinal fluid and ocular aqueous humor of rabbits

Zun-Yi Wang, Hans-Jürg Monstein, Kristian Waldeck, Lars Grundemar, Rolf Håkanson

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 126 KB

english, 1997

4

Characterization of vascular neuropeptide Y receptors

Lars Grundemar, S.E. Jonas, N. Mörner, Edward D. Högestätt, Claes Wahlestedt, Rolf Håkanson

Journal:

British Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.06 MB

english, 1992

5

Paracetamol analogues conjugated by FAAH induce TRPV1-mediated antinociception without causing acute liver toxicity

Ã.Nilsson, Johan L., Mallet, Christophe, Shionoya, Kiseko, Blomgren, Anders, Sundin, Anders P., Grundemar, Lars, Boudieu, Ludivine, Blomqvist, Anders, Eschalier, Alain, Nilsson, Ulf J., Zygmunt, Pete

Journal:

European Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.56 MB

2020

6

Neuropeptide Y Receptor Subtypes, Y1 and Y2

CLAES WAHLESTEDT, LARS GRUNDEMAR, ROLF HÅKANSON, MARKUS HEILIG, GREGORY H. SHEN, ZOFIA ZUKOWSKA-GROJEC, DONALD J. REIS

Journal:

Annals of the New York Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.09 MB

english, 1990

7

Suppression by neuropeptide Y of capsaicin-sensitive sensory nerve-mediated contraction in guinea-pig airways

Lars Grundemar, Nils Grundström, Irene G.M. Johansson, Rolf G.G. Andersson, Rolf Håkanson

Journal:

British Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 659 KB

english, 1990

8

Functional effects and ligand binding of chimeric galanin-neuropeptide Y (NPY) peptides on NPY and galanin receptor types

Ulrika Kahl, Ülo Langel, Tamas Bartfai, Lars Grundemar

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.17 MB

english, 1994

9

High Doses of Neuropeptide Y Reduce Blood Pressure in Anesthetized Rats

LARS GRUNDEMAR, CLAES WAHLESTEDT, GREGORY H. SHEN, ZOFIA ZUKOWSKA-GROJEC, ROLF HÅKANSON

Journal:

Annals of the New York Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 108 KB

english, 1990

10

Pharmacokinetics and bioavailability of a new testosterone gel formulation in comparison to Testogel® in healthy men

Olsson, Håkan, Sandström, Rikard, Neijber, Anders, Carrara, Dario, Grundemar, Lars

Journal:

Clinical Pharmacology in Drug Development

Year:

2014

Language:

english

File:

PDF, 269 KB

english, 2014

11

Effects of various neuropeptide Y/peptide YY fragments on electrically-evoked contractions of the rat vas deferens

Lars Grundemar, Rolf Håkanson

Journal:

British Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 561 KB

english, 1990

12

Neuropeptide Y: prejunctional inhibition of vagally induced contractions in the guinea pig trachea

Lars Grundemar, Erik Widmark, Bertil Waldeck, Rolf Håkanson

Journal:

Regulatory Peptides

Year:

1988

Language:

english

File:

PDF, 223 KB

english, 1988

13

Inhibition of stimulated cyclic AMP production by multiple neuropeptide Y receptors in the rat brainstem

Lars Ny, Lars Grundemar

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 100 KB

english, 1997

14

N,N’-Bis(2-mercaptoethyl)isophthalamide Binds Electrophilic Paracetamol Metabolites and Prevents Paracetamol-Induced Liver Toxicity

Nilsson, Johan L Å, Blomgren, Anders, Nilsson, Ulf J, Högestätt, Edward D, Grundemar, Lars

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2018

Language:

english

File:

PDF, 523 KB

english, 2018

15

Editorial Central & Peripheral Nervous Systems: Will neuropeptide Y receptor antagonists offer new therapeutic approaches?

Grundemar, Lars

Journal:

Expert Opinion on Therapeutic Patents

Year:

1995

File:

PDF, 808 KB

1995

16

Localization and activity of haem oxygenase and functional effects of carbon monoxide in the feline lower oesophageal sphincter

Lars Ny, Per Alm, Peter Ekström, Bengt Larsson, Lars Grundemar, Karl-Erik Andersson

Journal:

British Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.82 MB

english, 1996

17

Unlike VIP, the VIP-related peptides PACAP, helodermin and helospectin suppress electrically evoked contractions of rat vas deferens

Lars Grundemar, Rolf Håkanson

Journal:

Regulatory Peptides

Year:

1992

Language:

english

File:

PDF, 346 KB

english, 1992

18

Editorial Central & Peripheral Nervous Systems: Will neuropeptide Y receptor antagonists offer new therapeutic approaches?

Grundemar, Lars

Journal:

Expert Opinion on Therapeutic Patents

Year:

1995

Language:

english

File:

PDF, 808 KB

english, 1995

19

Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients

Russell, James A., Vincent, Jean-Louis, Kjølbye, Anne Louise, Olsson, Håkan, Blemings, Allan, Spapen, Herbert, Carl, Peder, Laterre, Pierre-Francois, Grundemar, Lars

Journal:

Critical Care (BioMed Central)

Year:

2017

Language:

english

File:

PDF, 695 KB

english, 2017

20

Unmasking the vasoconstrictor response to neuropeptide Y and its interaction with vasodilating agents in vitro

Lars Grundemar, Edward D. Högestätt

Journal:

European Journal of Pharmacology

Year:

1992

Language:

english

File:

PDF, 672 KB

english, 1992

21

Vascular effects of helodermin, helospectin I and helospectin II: a comparison with vasoactive intestinal peptide (VIP)

Lars Grundemar, Edward D. Högestätt

Journal:

British Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 498 KB

english, 1990

22

Suppression of sensory C fiber-mediated contractions by neuropeptide Y Y1 receptors in the guinea pig bronchi

Journal:

Regulatory Peptides

Year:

1998

Language:

english

File:

PDF, 112 KB

english, 1998

23

Ocular inflammation induced by electroconvulsive treatment: contribution of nitric oxide and neuropeptides mobilized from C-fibres

Zun-Yi Wang, Kristian Waldeck, Lars Grundemar, Rolf Håkanson

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 371 KB

english, 1997

24

Symptoms and signs of severe citalopram overdose

Lars Grundemar, Björn Wohlfart, Claes Lagerstedt, Finn Bengtsson, Göran Eklundh

Journal:

Year:

1997

Language:

english

File:

PDF, 18 KB

english, 1997

25

Effects of the Neuropeptide Y (NPY)-Receptor Antagonist BIBP3226 on Vascular NPY-Receptors with Different Ligand Requirements

Lars Grundemar, Mats Ekelund

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1996

Language:

english

File:

PDF, 409 KB

english, 1996

26

Risks in combination therapy of antidepressant drugs: Pharmacodynamic and kinetic interactions between antidepressant drugs may cause serious side-effects

Journal:

Trends in Pharmacological Sciences

Year:

1995

Language:

english

File:

PDF, 145 KB

english, 1995

27

Biphasic blood pressure response to neuropeptide Y in anesthetized rats

Lars Grundemar, Claes Wahlestedt, Gregory H. Shen, Zofia Zukowska-Grojec, Rolf Håkanson

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 265 KB

english, 1990

28

Inhibition by zinc protoporphyrin-IX of receptor-mediated relaxation of the rat aorta in a manner distinct from inhibition of haem oxygenase

Lars Ny, Karl-Erik Andersson, Lars Grundemar

Journal:

British Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 804 KB

english, 1995

29

Carbon monoxide as a putative messenger molecule in the feline lower oesophageal sphincter of the cat

Ny, Lars, Grundemar, Lars, Larsson, Bengt, Alm, Per, Ekström, Peter, Andersson, Karl-Erik

Journal:

Year:

1995

File:

PDF, 317 KB

1995

30

Effect of Degarelix, a Gonadotropin-Releasing Hormone Receptor Antagonist for the Treatment of Prostate Cancer, on Cardiac Repolarisation in a Randomised, Placebo and Active Comparator Controlled Thorough QT/QTc Trial in Healthy Men

Olsson, Håkan, Petri, Niclas, Erichsen, Lars, Malmberg, Anders, Grundemar, Lars

Journal:

Clinical Drug Investigation

Year:

2017

Language:

english

File:

PDF, 631 KB

english, 2017

31

Characterization of Y3 receptor-mediated synaptic inhibition by chimeric neuropeptide Y-peptide YY peptides in the rat brainstem

Steven R. Glaum, Richard J. Miller, Hyewhon Rhim, Derek Maclean, Ynn M. Georgic, Robert G. MacKenzie, Lars Grundemar

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 473 KB

english, 1997

32

Multiple neuropeptide Y receptors are involved in cardiovascular regulation. Peripheral and central mechanisms

Lars Grundemar, Rolf Håkanson

Journal:

General Pharmacology: The Vascular System

Year:

1993

Language:

english

File:

PDF, 1.01 MB

english, 1993

33

C-terminal neuropeptide Y fragments are mast cell-dependent vasodepressor agents

Gregory H. Shen, Lars Grundemar, Zofia Zukowska-Grojec, Rolf Håkanson, Claes Wahlestedt

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 967 KB

english, 1991

34

Pitfalls using metalloporphyrins in carbon monoxide research

Lars Grundemar, Lars Ny

Journal:

Trends in Pharmacological Sciences

Year:

1997

Language:

english

File:

PDF, 379 KB

english, 1997

35

Neuropeptide Y, peptide YY and C-terminal fragments release histamine from rat peritoneal mast cells

Lars Grundemar, Rolf Håkanson

Journal:

British Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 622 KB

english, 1991

36

Characterization of the receptor response for the neuropeptide Y-evoked suppression of parasympathetically-mediated contractions in the guinea pig trachea

Journal:

Regulatory Peptides

Year:

1997

Language:

english

File:

PDF, 113 KB

english, 1997

37

Different pharmacokinetic and pharmacodynamic properties of recombinant follicle-stimulating hormone (rFSH) derived from a human cell line compared with rFSH from a non-human cell line

Olsson, Håkan, Sandström, Rikard, Grundemar, Lars

Journal:

Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 272 KB

english, 2014

38

Long-lasting inhibition of the cardiovascular responses to glutamate and the baroreceptor reflex elicited by neuropeptide Y injected into the nucleus tractus solitarius of the rat

Grundemar, Lars, Wahlestedt, Claes, Reis, Donald J.

Journal:

Neuroscience Letters

Year:

1991

Language:

english

File:

PDF, 459 KB

english, 1991

39

Activation of neuropeptide Y1 and neuropeptide Y2 receptors by substituted and truncated neuropeptide Y analogs: identification of signal epitopes

Lars Grundemar, John L. Krstenansky, Rolf Håkanson

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 780 KB

english, 1993

40

Neuropeptide Y suppresses the neurogenic inflammatory response in the rabbit eye; mode of action

Lars Grundemar, Claes Wahlestedt, Zun-Yi Wang

Journal:

Regulatory Peptides

Year:

1993

Language:

english

File:

PDF, 564 KB

english, 1993

41

Modulation of carbon monoxide production and enhanced spatial learning by tin protoporphyrin

Bing, Ola, Grundemar, Lars, Ny, Lars, Möller, Christian, Heilig, Markus

Journal:

Year:

1995

File:

PDF, 321 KB

1995

42

Cloning and functional expression of the guinea pig neuropeptide Y Y2 receptor

Parul Sharma, Sara K.S Holmberg, Henrik Eriksson, Annette G Beck-Sickinger, Lars Grundemar, Dan Larhammar

Journal:

Regulatory Peptides

Year:

1998

Language:

english

File:

PDF, 270 KB

english, 1998

43

Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function

Bo Ding, Björn Kull, Zhurong Liu, Salim Mottagui-Tabar, Håkan Thonberg, Harvest F. Gu, Anthony J. Brookes, Lars Grundemar, Christina Karlsson, Anders Hamsten, Peter Arner, Claes-Göran Östenson, Suad E

Journal:

Regulatory Peptides

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

44

Characterisation of Population Pharmacokinetics and Endogenous Follicle-Stimulating Hormone (FSH) Levels After Multiple Dosing of a Recombinant Human FSH (FE 999049) in Healthy Women

Rose, Trine Høyer, Röshammar, Daniel, Erichsen, Lars, Grundemar, Lars, Ottesen, Johnny T.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.27 MB

english, 2016

45

Neuropeptide Y and truncated neuropeptide Y analogs evoke histamine release from rat peritoneal mast cells. A direct effect on G proteins?

Lars Grundemar, John L. Krstenansky, Rolf Håkanson

Journal:

European Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 337 KB

english, 1994

46

Functional Effects of Neuropeptide Y Receptors on Blood Flow and Nitric Oxide Levels in the Human Nose

CERVIN, ANDERS, ÖNNERFÄLT, JENNY, EDVINSSON, LARS, GRUNDEMAR, LARS

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

1999

Language:

english

File:

PDF, 231 KB

english, 1999

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